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Paclitaxel (2mg/kg per treatment, black circles) induced mechanical hypersensitivity in the glabrous skin of the hindpaw (A) but not in the hairy skin of the dorsal hindpaw (B) or inner thigh (C), as assessed with an electronic Von Frey device. No changes in mechanical threshold were observed in vehicle treated (grey circles) animals. Paclitaxel/vehicle were administered at the points indicated with gray arrows n = 7 per group.
