Table 4.

Redox Potentials (E_1/2 vs SCE) of Model Compounds vs Nitrile Hydratase

	DMF		CH3CN		H2O
	E1/2 (V)	ΔE (mV)	E1/2 (V)	ΔE (mV)	E1/2 (V)	ΔE (mV)
[FeIII(DITpy)2]+ (1)a			−0.93	90	−0.74	60
[FeIII(DITIm)2]+ (2)a			−0.68	350
[FeIII(ADIT)2]+ (3)a			−1.02	90	−0.77	60
[FeIII(AMIT)2]+ (4)a			−0.86	90
[FeIII(PyAS)2]+b	−0.13	60
[FeIII(PyMS)2]+b	−0.51	NRf
[FeIII(PyPepS)2]+c	−1.12	120
NHase enzymed,e					−0.48	NRf

^aThis work.

^bNoveron, J. C.; Herradora, R.; Olmstead, M. M.; Mascharak, P., K. Inorg. Chim. Acta. 1999, 285, 269–276.

^cNoveron, J. C.; Olmstead, M. M.; Mascharak, P. K. Inorg. Chem. 1998, 37, 1138–1139.

^dNHase enzyme from Rhodococcus sp. R312 in the presence of butyric acid.

^eArtaud, I.; Chatel, S.; Chauvin, A. S.; Bonnet, D.; Kopf, M. A.; Leduc, P. Coord. Chem. ReV. 1999, 192, 577–586.

^fNR = not reported.