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. 2015 May 6;47(1):71–80. doi: 10.3892/ijo.2015.2989

Figure 2.

Figure 2

Combined treatment with PD0325901 and temsirolimus inhibits tumor growth. (A) Growth curves of tumorgrafts treated with PD0325901 (3.5 mg/kg) plus temsirolimus (1.87 mg/kg) (n=7), PD0325901 (n=8), temsirolimus (n=8), vehicle (n=8), and non-treated (n=7). (B) At treatment day 38, tumorgrafts treated with PD0325901 plus temsirolimus were significantly smaller than those treated with either PD0325901 or temsirolimus alone. Error bars represent standard deviation. Significance was determined by Wilcoxon rank sum for unmatched pairs. *p<0.005.