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. 2015 Jun 19;21:1774–1780. doi: 10.12659/MSM.893458

Figure 1.

Figure 1

MiR-15b expression is significantly lower, while IL-15 is significantly higher in MG patients and EAMG rats. (A, B) qRT-PCR anlysis of miR-15b and ELISA of serum IL-15. Compared with healthy controls (n=20), expression of miR-15b (A) was significantly lower, while IL-15 (B) was significantly higher in EMG (n=20), LMG (n=22), and thymoma cases (n=15) than in healthy controls. (C, D) qRT-PCR anlysis of miR-15b in serum (C) and EDL muscle (D) of mice. Compared with healthy mice, EAMG mice had signficiantly lower miR-15b in both serum and muscle. (E, F) ELISA of IL-15 in serum (C) and EDL muscle (D) of mice. Compared with healthy mice, EAMG mice had signficiantly higher IL-15 in both serum and muscle. Error bars indicates standard deviation (SD). * P<0.05, ** P<0.01, *** P<0.001.