Skip to main content
. 2015 Jun 4;78(6):1330–1338. doi: 10.1021/acs.jnatprod.5b00187

Table 3. Bioactivities of 5,6-Dihydro-α-pyrones 15.

  1 2 3 4 5 artemisinin taxol
Dd2 IC50 (μM)a 9.2 ± 0.9 5.8 ± 1.4 5.5 ± 0.7 7.4 ± 0.6 9.0 ± 3.0 0.007 ± 0.001 N/A
A2780 IC50 (μM)b >10 >10 8.6 >10 >10 N/A 0.028 ± 0.002
a

Antimalarial activity against the Dd2 strain of Plasmodium falciparum

b

Antiproliferative activity against human ovarian cancer cells.