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. 2015 Jun 4;78(6):1330–1338. doi: 10.1021/acs.jnatprod.5b00187

Table 4. Bioactivities of Bicyclic Tetrahydro-α-pyrone Derivatives 611.

  6 7 8 9 10 11 artemisinin taxol
Dd2 IC50 (μM)a 4.0 ± 2.0 6.0 ± 0.5 >10 >10 >10 >10 0.007 ± 0.001 N/A
A2780 IC50 (μM)b >10 >10 >10 >10 >10 >10 N/A 0.028 ± 0.002
a

Antimalarial activity against the Dd2 strain of Plasmodium falciparum

b

Antiproliferative activity against human ovarian cancer cells.