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. 2015 May 13;4(7):e1014232. doi: 10.1080/2162402X.2015.1014232

Figure 2.

Figure 2.

Diminished antitumor T-cell responses in IL-10−/− mice. (A) Established J558 tumors from WT and IL-10−/− mice were harvested and single-cell suspensions were prepared and stained for CD4 and CD8, followed by flow cytometry analysis. The percentage of CD4+ and CD8+ T lymphocytes in tumors from WT and IL-10−/− mice are summarized (n = 9 per group). Data shown are representative of 3 experiments with similar results. (B) IFN-γ producing CD8+ and CD4+ T cells in tumors from WT and IL-10−/− mice were analyzed and quantified by flow cytometry. The percentage of IFN-γ–producing CD4+ and CD8+ T lymphocytes in tumors from WT and IL-10−/− mice is summarized (n = 7 per group). Data shown are representative of 3 experiments with similar results.