Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Summary of GVL experiments. WT and Ik-deficient host APCs showed an equivalent GVL effect for P185, Ik-WT tumor. However, Ik deficiency in both hematopoietic APCs and leukemia cells ameliorates GVL responses
| APC/Tumor | P185 (Ik WT) | Ik6 (Ik DN mutation) |
|---|---|---|
| WT APC | ++ | ++ |
| Ik−/− APC | ++ | + |
