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. 2015 May 16;76(1):75–84. doi: 10.1007/s00280-015-2757-0

Table 4.

Adverse events

n (%)
Grade ≥1 Grade ≥3
Neutropenia 441 (53.3 %) 238 (28.7 %)
Leucopenia 265 (32.0 %) 21 (2.5 %)
Thrombocytopenia 264 (31.9 %) 14 (1.7 %)
Diarrhea 153 (18.5 %) 17 (2.1 %)
Anorexia 255 (30.8 %) 17 (2.1 %)
Nausea 311 (37.6 %) 14 (1.7 %)
ALT (GPT) increased 199 (24.0 %) 13 (1.6 %)
Fatigue 205 (24.8 %) 10 (1.2 %)
Vomiting 90 (10.9 %) 6 (0.7 %)
AST (GOT) increased 211 (25.5 %) 5 (0.6 %)
Febrile neutropenia 3 (0.4 %) 3 (0.4 %)
Pneumonitis (interstitial pneumonitis) 7 (0.8 %) 1 (0.1 %)

CTCAE version 4.0