Table 4.

Adverse events

	n (%)
	Grade ≥1	Grade ≥3
Neutropenia	441 (53.3 %)	238 (28.7 %)
Leucopenia	265 (32.0 %)	21 (2.5 %)
Thrombocytopenia	264 (31.9 %)	14 (1.7 %)
Diarrhea	153 (18.5 %)	17 (2.1 %)
Anorexia	255 (30.8 %)	17 (2.1 %)
Nausea	311 (37.6 %)	14 (1.7 %)
ALT (GPT) increased	199 (24.0 %)	13 (1.6 %)
Fatigue	205 (24.8 %)	10 (1.2 %)
Vomiting	90 (10.9 %)	6 (0.7 %)
AST (GOT) increased	211 (25.5 %)	5 (0.6 %)
Febrile neutropenia	3 (0.4 %)	3 (0.4 %)
Pneumonitis (interstitial pneumonitis)	7 (0.8 %)	1 (0.1 %)

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