FIG. 3.

miR-134 inhibits epithelial–mesenchymal transition (EMT) in RCC cells. (A, B) Overexpression of miR-134 inhibited migration and invasion in RCC cell lines. (C) Western blot analysis was used to detect the changes in EMT markers in 786-O and caki-1 cells treated with miR-134 mimics. A gain in E-cadherin expression and a loss of N-cadherin and vimentin were observed in treated cells. Data are mean±SD of at least three independent experiments. *p<0.05 compared with the mock or negative control group. Original magnification 200×. GAPDH, glyceraldehyde-3-phosphate dehydrogenase; SD, standard deviation.