Table 3.
Results from bivariate and multivariable logistic regression modeling of demographic and clinical factors associated with achievement of enteral autonomy in children with intestinal failure (n=272). Model 1 includes data from all 272 children; model 2 includes only those children with intra-operatively measured residual small bowel length (n=144).
Model | Characteristics | Bivariate OR (95% CI) | P Value1 | Multivariable OR (95% CI) | P Value2 |
---|---|---|---|---|---|
| |||||
Model 1: all children, n=272 | NEC | 0.005 | 0.004 | ||
No | Reference | Reference | |||
Yes | 2.64 (1.53, 4.55) | 2.42 (1.33, 4.47) | |||
| |||||
ITx Site | <0.001 | <0.001 | |||
Yes | Reference | Reference | |||
No | 2.86 (1.70, 4.79) | 2.73 (1.56,4.78) | |||
| |||||
Preserved ICV | <0.001 | <0.001 | |||
No | Reference | Reference | |||
Yes | 2.48 (1.49, 4.12) | 2.80 (1.63, 4.83) | |||
| |||||
Model 2: measured bowel length, n=144 | NEC | 0.002 | 0.009 | ||
No | Reference | Reference | |||
Yes | 3.22 (1.54,6.73) | 3.44 (1.36, 8.71) | |||
| |||||
ITx Site | <0.001 | <0.001 | |||
Yes | Reference | Reference | |||
No | 7.91(3.44,18.18) | 6.56 (2.53,16.98) | |||
| |||||
Residual small bowel length | 1.04 (1.03,1.06) | <0.001 | 1.04 (1.02,1.06) | <0.001 | |
Preserved ICV | 0.02 | 0.36 | |||
No | Reference | Reference | |||
Yes | 2.21(1.12, 4.34) | 1.52 (0.62, 3.74) |
OR (95% CI) and p-value obtained from separate logistic regression models with each characteristic considered as a single predictor of achievement of enteral autonomy.
OR (95% CI) and p-value obtained from multivariable logistic regression model with all characteristics considered as predictors of achievement of enteral autonomy. Variables selected for inclusion in the model using a forward-selection type model building procedure, beginning by ranking the variables by significance level. Model includes only those children with intraoperatively measured residual small bowel length.