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The metabolic pathway of gamma-aminobutyric acid (GABA) and potential targets for therapeutic trials in SSADH deficiency.
GAD = glutamic acid decarboxylase
P5P = pyridoxal-5’-phosphate
VGB = vigabatrin
GABA-T = GABA-transaminase
SSADH = succinic semialdehyde dehydrogenase
GABABR = GABAB receptor
GABAAR = GABAA receptor
mTOR = mammalian target of rapamycin
