For each interactor observed to bind both Ssa1 and Hsp82 in this study, change in association for Ssa1 (Ln ratio, X-axis) vs. change in association for Hsp82 (Ln ratio, Y-axis) was plotted. The dotted lines represent an interaction change of up or down two-fold. Interactors are colored according to significant change in chaperone association upon DNA damage as follows: blue (increased with both chaperones), brown (decreased with both chaperones), yellow (decreased with Ssa1), green (decreased with Hsp82), grey (increased with Hsp82), or black (no significant change with either chaperone).