Table 1.
Baseline characteristics of study participants (n = 298,468)
| Total cohort | Any aspirin users |
Any nonaspirin NSAID users |
Neither | Aspirin only |
Nonaspirin NSAIDs only |
Both aspirin and nonaspirin NSAIDs |
Either aspirin, nonaspirin NSAIDs, or both |
|
|---|---|---|---|---|---|---|---|---|
|
n = 298,468 % |
n = 218,372 % |
n = 168,414 % |
n = 40,173 % |
n = 89,881 % |
n = 39,923 % |
n = 128,491 % |
n = 258,295 | |
| Age, years, mean (SD) | 62.8 (5.3) | 62.8 (5.3) | 62.2 (5.4) | 63.6 (5.1) | 63.5 (5.1) | 62.1 (5.4) | 62.3 (5.4) | 62.7 (5.3) |
| Male | 58.4 | 62.6 | 55.7 | 53.3 | 65.8 | 40.4 | 60.4 | 59.2 |
| Race | ||||||||
| White | 92.5 | 93.4 | 93.0 | 88.9 | 93.3 | 91.4 | 93.5 | 93.1 |
| Black | 3.3 | 2.7 | 3.1 | 5.4 | 2.7 | 4.5 | 2.7 | 3.0 |
| Others | 4.2 | 3.9 | 3.9 | 5.7 | 4.0 | 4.1 | 3.8 | 3.9 |
| Married | 68.2 | 70.2 | 68.6 | 62.9 | 69.8 | 62.4 | 70.5 | 69.0 |
| First-degree relative diagnosed with any cancer |
49.4 | 49.2 | 50.3 | 48.5 | 48.2 | 51.4 | 50.0 | 49.6 |
| Rigorous physical activity | ||||||||
| Never or rarely | 16.8 | 15.6 | 16.3 | 20.7 | 16.1 | 19.7 | 15.2 | 16.2 |
| 1–3 times per month | 13.3 | 13.3 | 13.8 | 12.6 | 12.6 | 13.7 | 13.8 | 13.4 |
| 1–2 times per week | 21.4 | 21.8 | 21.9 | 19.7 | 21.3 | 21.1 | 22.1 | 21.7 |
| 3–4 times per week | 27.6 | 28.2 | 28.0 | 25.5 | 27.7 | 26.3 | 28.6 | 27.9 |
| ≥5 times per week | 20.1 | 20.3 | 19.3 | 20.4 | 21.5 | 18.4 | 19.6 | 20.0 |
| Unknown | 0.8 | 0.8 | 0.7 | 1.1 | 0.8 | 0.8 | 0.7 | 0.8 |
| College graduate and postgraduate | 64.4 | 66.0 | 66.1 | 58.4 | 63.8 | 61.4 | 67.6 | 65.3 |
| Tobacco smoking | ||||||||
| Never | 35.9 | 35.0 | 35.5 | 38.9 | 35.3 | 37.9 | 34.7 | 35.4 |
| Former | 49.8 | 50.9 | 50.6 | 46.3 | 49.9 | 47.4 | 51.7 | 50.4 |
| Current | 11.0 | 10.8 | 10.6 | 11.4 | 11.5 | 11.6 | 10.3 | 10.9 |
| Unknown | 3.3 | 3.3 | 3.3 | 3.4 | 3.3 | 3.1 | 3.3 | 3.3 |
| Self-reported history of hypertension |
39.0 | 39.6 | 38.7 | 38.0 | 40.2 | 37.0 | 39.2 | 39.2 |
| Self-reported history of diabetes | 8.4 | 8.4 | 8.1 | 9.4 | 8.7 | 7.8 | 8.2 | 8.3 |
| Current body mass index, Kg/m2 (SD) |
26.9 (5.0) | 26.9 (4.9) | 27.2 (5.1) | 26.7 (5.3) | 26.6 (4.7) | 27.3 (5.6) | 27.2 (5.0) | 27.0 (5.0) |
| Alcohol, gram per day, mean (SD) | 13.1 (36.0) | 13.8 (36.3) | 12.8 (34.5) | 11.6 (37.6) | 14.2 (38.1) | 10.8 (32.7) | 13.4 (35.0) | 13.3 (35.8) |
| Total dietary fiber, gram, mean (SD) |
19.7 (10.6) | 19.8 (10.5) | 19.5 (10.4) | 20.1 (11.7) | 19.9 (10.4) | 18.8 (10.0) | 19.7 (10.5) | 19.6 (10.4) |