. Author manuscript; available in PMC: 2015 Jun 30.

Published in final edited form as: Cancer Gene Ther. 2012 Mar 9;19(5):336–344. doi: 10.1038/cgt.2012.6

Table 3.

ISF35 mRNA expression in tissues positive for Ad-ISF35 DNA presence

	Tissue	ISF35 mRNA copy number per 100 ng cDNA
One injection
3 × 10⁹	Tumor	14
	Tumor	<5
	Tumor	NS
	Tumor	NS
	Lymph nodes	<5
3 × 10¹⁰	Tumor	11
	Tumor	68
	Tumor	21
	Tumor	19
	Tumor	<5
	Tumor	<5
	Lymph nodes	NS
	Gonads	<5
Three injections
3 × 10⁹	Tumor	<5
3 × 10¹⁰	Tumor	<5
	Tumor	NS
	Tumor	NS
	Spleen	<5
	Spleen	<5
	Kidney	<5
	Kidney	11
Follow-up 3 × 10¹⁰	Tumor	40
	Spleen	<5
	Spleen	<5

Abbreviations: Ad, adenovirus; NS, no sample was available because tumor tissue was very small (due to tumor regression) and enough only for DNA extraction.