Fluorinated pyrimidines (5 fluorouracil, capecitabine, tegafur-uracil, S1) |
Vasospasm, arterial, and venous thrombosis |
Cisplatin |
Endothelial damage, Raynaud’s phenomenon, thrombosis (often combined with dexamethasone as an antiemetic) |
L-asparaginase |
Alters plasma levels of procoagulants and anticoagulants (AT III, protein C, protein S) |
Tamoxifen |
Alters plasma levels of coagulation factors |
Dexamethasone |
Alters plasma levels of coagulation factors |
Erythropoiesis-stimulating agents |
Alters plasma levels of coagulation factors, increased tissue factor expression |
ImiDs (thalidomide, lenalidomide, etc.) |
Endothelial damage, altered plasma levels of F. VIII, von Willebrand factor |