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. 2015 Jun 1;34(6):437–457. doi: 10.1089/dna.2014.2687

Table 3.

The List of Predicted Target Genes of Differentially Expressed C19MC microRNAs in Gestational Hypertension, Preeclampsia, and Fetal Growth Restriction in Relation to the Immune System and the Inflammatory Response

microRNA miR-515-5p miR-517-5p miR-518b miR-518f-5p miR-519a miR-519d miR-520a-5p miR-520h miR-524-5p miR-525 miR-526a
Number of predicted target genes 571 239 30 215 685 844 486 462 916 482 215
Unique target genes API5 FAS CD5 LILRA1 BAG5 BCL10 ELF4 DIDO1 API5 TOX BCAP29
  CIAPIN1 IL9R PRDX6 EGLN3 CD69 CASP2 CCL7 IFNAR1 BCL10 OLR1 CD302
  HSPA12A IRAK3 TOLLIP FLT3 CXCL12 CD69 SOCS3 PIAS2 CD276 IGF1R DNAJC21
  HSPH1 LILRA2   TLR6 DNAJB9 CD84 OLR1 RFX4 CD47 TLR7 HSP90AA1
  IL16 MTDH   TNFRSF19 FZD6 DNAJB6 IGF1R TGFB2 CD8A ACVR2B IGFBP1
  IL6R PAPPA   CXCL11 HIF1A HSPA8 TLR7 THAP2 HSPA1B ATRN TLR2
  TNFAIP8L1 BCLAF1a (Yoshitomi et al.,2011)   TNFSF4 HSPA13 IL17RD ACVR2B TLR5 IL1A CD2 TNFRSF19
  XIAP IFNA1   ADAM19 HSPA8 IL8 ATRN CD38 IL1RL1 CD300LB TNFSF15
  CASP10 IL6   TLR2 IER3IP1 MCL1 CD2 SMAD6 SMAD4 CD46 TRAF6
  CD46 NFKB1   ADAM9 NFAT5 PDCD1LG2 CD300LB TGFBR2 SMURF2 CD93  
  ATRN CASP10     PDCD1LG2 SMAD5 CD46 VEGFAa (Ye et al.,2008) SOCS4 HSF5  
  IL10RA BCL2     TNF TGFBR2 CD93 HIF1A TNFAIP1 IL10RA  
  TGFBR2       TNFRSF10D TNFAIP1 HSF5 PAFAH1B2 CD46 MMD2  
          BBC3 TNFSF11 IL10RA BNIP3L CD1A PPARA  
          BCL2L2a (Huang et al.,2011) BID MMD2 IRAK4 IRAK2 AHSA2  
          CASP3a (Huang et al.,2011) CPAMD8 PPARA SMAD2 IRAK4    
          CISH PPARAa (Martinelli et al.,2010) AHSA2 SMAD3 SMAD2    
          FLT1 TNFRSF1A   SMAD7 SMAD3    
          BCL2a (Huang et al.,2011) TP53a (Fornari et al., 2012)          
          BNIP3La (Ye et al.,2008) F3          
          IRAK2 HIF1A          
          SMAD7 PAFAH1B2          
          TGFBR2 BNIP3L          
          TNFRSF21 IRAK4          
          TOLLIP SMAD7          
            TNFRSF21          
a

Experimentally verified targets according to miRWalk database.