ROC curves of the 22 TAAs in discriminating between HCC and controls and representative scatter diagram of signal intensity of CENPF, HSP60 and IMP-2. Upper panel: ROC curve for the 22 TAAs. A. 12 of the 22 TAAs with p-values < 0.05. B. 10 of the 22 TAAs with p-values > 0.05. Lower panel, scatter diagrams: signal intensity in early-HCC, HCC, LC, CH, HC and other cancers. C. CENPF. D. HSP60. E. IMP-2. Black horizontal lines indicate means, and error bars are SEs. ROC, receiver operating characteristic. HCC, hepatocellular carcinoma; LC, liver cirrhosis; CH, chronic hepatitis; HC, healthy controls.