TABLE 3.
Rat Chow Diet | 0 IU/g Vitamin D deficient D3, ‘DD’ Ca = 0.95% | 2.25 IU/gVitamin D insufficient D3, ‘ID’ Ca = 0.95% | 5 IU/g Vitamin-D sufficient D3, control diet ‘CD’ Ca = 0.95% | 40 IU/g Vitamin D hyper-vitamin D3, ‘HD’, Ca = 0.94% |
---|---|---|---|---|
Weights (I_wt g, at intake) | 271.00 ± 4.80 | 272.50 ± 4.17 | 270.00 ± 7.04 | 270.50 ± 7.69 |
Weights (Srg_wt g, at surgery) | 421.64 ± 83.27 | 446.42 ± 34.54 | 424.15 ± 70.61 | 431.42 ± 70.99 |
Weights (Sac_wt g, at sacrifice) | 589.71 ± 19.18 | 576.11 ± 44.30 | 578.56± 34.09 | 601.00 ±10.90 |
Serum Vitamin D (sVD, at surgery)* | 9.25 ± 1.61 | 20.64 ± 3.27 | 28.30± 4.57 | 97.37± 13.59 |
Serum Vitamin D (sVD at sacrifice)* | 6.25 ± 1.02 | 15.58 ± 5.04 | 19.59 ± 5.64 | 88.44 ± 9.90 |
Serum Calcium-Total (CaT,, at sacrifice) | 11.69 ± 1.20 | 11.78 ± 0.49 | 11.48 ± 0.89 | 12.86 ± 0.76 |
Serum Calcium-Free (CaF, at sacrifice) | 6.59 ± 0.85 | 6.83 ± 0.81 | 6.84 ± 1.07 | 7.11 ± 1.09 |
Serum Calcium-Bound (CaB, at sacrifice) | 5.10 ± 1.74 | 4.95 ± 0.72 | 4.65 ± 1.29 | 5.75 ± 1.15 |
p<0.0001 overall
Intracorrelations among dietary and serum status variables:
Vitamin D adjusted diet and serum Total Ca: dVD3 vs. sCaT, r=0.52, p<0.0002;
Serum Vitamin D and serum Total Ca: sVD vs. sCaT, r=0.51, p<0.0002;
Marginal correlation between Serum Vitamin D and serum Bound Ca: sVD vs. sCaB, r=0.25, p=0.08;
Correlation between serum Total Ca and serum Bound Ca: sCaT vs. sCaB, r=0.68, p<0.0001;
Correlation between sCaF and sCaB (r= −0.64, p<0.0001)