TABLE 4.
Rat Chow Diet | 0 IU/g Vitamin D deficient D, ‘DD’ | 2.25 IU/g Vitamin D insufficient D, ‘ID’ | 5 IU/g Vitamin-D sufficient D, ‘CD’ | 40 IU/g Vitamin-D hyper-vitamin D, ‘HD’ | p-value |
---|---|---|---|---|---|
Biomechanical Stiffness (Nmm/mm) , average ± sd | 463.99±76.67 (n=5) | 385.67 ± 75.78 (n=7) | 494.04±86.17 (n=8) | 503.91 ± 67.44 (n=10) | p<0.01 |
U.CT Bone Mineral Density (BMD), average ± sd | 409.98±58.40 | 422.36±37.11 | 441.00±40.53 | 483.83±56.50 | p<0.01 |
U.CT Mineralized Bone Volume (BV) average ± sd | 575.58 ± 81.00 | 488.27 ± 87.27 | 512.97 ± 110.14 | 651.61 ± 162.71 | P<0.01 |
U.CT Bone Volume Measures (BS/BV), average ± sd | 4.91±0.86 | 4.81±0.51 | 4.44±0.48 | 3.83 ± 0.65 | p<0.01 |
U.CT Bone Volume Fraction (BV/TV), average ± sd | 0.71±0.09 | 0.74±0.051 | 0.76±0.05 | 0.81 ± 0.05 | p<0.01 |
For pairwise comparison: **p<0.05, Tukey stiffness: HD vs.ID, CD vs.ID; ** p<0.05, Tukey: BMD: HD vs. ID, HD vs. DD; ** p<0.05, Tukey: μ.CT BV: HD vs.CD, HD vs. ID; **p<0.05, Tukey: μCT BS/BV: HD vs. ID, HD vs. DD; ** p<0.05 Tukey: μ.CT BV/TV: HD vs. ID, HD vs. DD.