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. Author manuscript; available in PMC: 2015 Oct 25.
Published in final edited form as: Chem Commun (Camb). 2015 Mar 23;51(32):6948–6951. doi: 10.1039/c4cc09920f

Fig. 3.

Fig. 3

Real-time reporting of CPT release from CPT-SS-CyN in female athymic nude mice bearing human A375 melanoma. (a) Fluorescence spectra (CyN channel) of tumor tissues and whole body NIR fluorescence images of athymic nude mice bearing human A375 melanoma following a single intratumoral injection of CPT-SS-CyN (5 nmol/tumor, the scale bar is 1.0 cm). Images taken at 10 min, 2 h, and 5 h by a Maestro in vivo whole-animal fluorescence imaging system (excitation at 615-665 nm, emission at 680-950 nm) were shown. (b) Average fluorescence intensity profile at 740 nm of tumor tissues after injection of CPT-SS-CyN.