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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pharmacoepidemiol Drug Saf. 2014 Mar 24;23(6):628–635. doi: 10.1002/pds.3609

Table 3.

Weighted sensitivity, specificity, and positive predictive value (PPV) of the antipsychotic polypharmacy claims-based measure in a random sample of Medicaid mental health clinic clients (n = 312)

Validation criterion: medical record-based measure
Antipsychotic
polypharmacy
No antipsychotic
polypharmacy
Total Sensitivity (95%CI) Specificity (95%CI) PPV (95%CI)
Medicaid claims-based measure Antipsychotic polypharmacy 36 3 39 81.8% (67.7-91.8) 98.8% (96.7-99.7) 92.3% (79.1-98.4) Raw
No antipsychotic polypharmacy 8 265 273 79.4% (70.4-86.6) 99.1% (98.2-99.6) 90.9% (83.1-95.9) Weighted
Total 44 267 312

Notes:

95% exact binomial confidence intervals were calculated for each proportion. Weighted results reflect the underlying sampling probability.

Antipsychotic polypharmacy: two or more antipsychotics for longer than 90 days, as of 1/4/2008.

No antipsychotic polypharmacy: did not meet criteria for antipsychotic polypharmacy, as of 1/4/2008.