Skip to main content
. 2015 Feb 9;33(20):2231–2238. doi: 10.1200/JCO.2014.58.5828

Fig 3.

Fig 3.

(A) Cumulative incidence of local, regional, and distant failure and second primary tumor (SPT) per Radiation Therapy Oncology Group RTOG-0630 (A Phase II Trial of Image-Guided Preoperative Radiotherapy for Primary Soft Tissue Sarcomas of the Extremity) definitions of failure. (B) Kaplan-Meier estimates of disease-free survival (DFS) and distant disease-free survival per RTOG-0630 definitions of failure. (C) Kaplan-Meier estimates of local recurrence, regional/distant recurrence, and progression-free survival (PFS) per National Cancer Institute of Canada SR2 (CAN-NCIC-SR2; Phase III Randomized Study of Pre- vs Postoperative Radiotherapy in Curable Extremity Soft Tissue Sarcoma) definitions of failure. (D) Kaplan-Meier estimates of overall survival. In the CAN-NCIC-SR2 trial, patients who did not have surgery or had an amputation to remove the primary tumor were not included in analysis, so (C) has fewer patients (73) than (A), (B), and (D), which have 79. Event No. indicates distant, local, or regional failure or second primary.