Table 4.

Treatment Parameters for Five In-Field Local Recurrences

Tumor Size (cm)	Central Review			Postoperative Radiation Boost	Radiation Review Score
	Histologic Grade	Histology	Resection Status		Target Volume	Target Volume Dose Volume Analysis
3.7	3	Leiomyosarcoma	0	No	Acceptable variation	Per protocol
6.1	3	Malignant peripheral nerve sheath tumor, spindle cell	1	No	Acceptable variation	Unacceptable variation
7.2	3	Undifferentiated pleomorphic sarcoma	1	Yes	Per protocol	Per protocol
12.0	3	Undifferentiated pleomorphic sarcoma	1	Yes	Unacceptable variation*	Unacceptable variation
16.5	3	Pleomorphic leiomyosarcoma	0	No	Unacceptable variation†	Per protocol

Abbreviations: GTV, gross tumor volume.

^*Unacceptable variation: gross tumor volume deviation unacceptable (includes edema). Clinical tumor volume deviation unacceptable (includes excessive subcutaneous tissue). Planning target volume deviation unacceptable (not adequate expansion per protocol), overall score not acceptable.

^†Unacceptable variation: GTV deviation unacceptable; slice 4.5, 3.5, and 2.5 cm GTV too tight anteriorly; GTV not covering tumor anteriorly compared with magnetic resonance imaging; overall score not acceptable.