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(a) SN-38 release from CSPT NPs in the presence of DTT treatment. (b) Cytotoxicity of CSPT NPs in HeLa cells. Standard MTT protocol was followed by incubating drug solutions with cells for 72 hours. Data are presented as mean value±standard deviation of 3 measurements. (c) Representative images of (TUNEL) assay for apoptotic index analysis. Apoptotic cells were stained as red and cell nuclei were stained as blue. Scale bar: 100 μm.
