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siRNA delivery by PAMD-Ch in U2OS cells. Transfections were conducted either in the absence (a) or the presence of 10% serum (b). Polyplexes were prepared with control siScr (left) or siPLK1 (right) at various equivalent PAMD/siRNA w/w ratios and cell killing mediated by PLK1 knockdown was measured (n = 4).
