Table 2.
Results from von Frey linear model.
Cluster or ROI name | Side | Coordinates of peak(s) voxel¥ | Peak region | Peak t-value | VF partial correlation corrected for age† | |
---|---|---|---|---|---|---|
SNI (df=45) | Sham (df=27) | |||||
S1HL/M1 | Right | 1.8, −1.1, 8.8 | M1 | 3.92 | 0.400** | −0.013 |
S1HL/M1 | Left | −2.2, −1.1, 8.8 | S1HL | 3.35 | 0.334* | −0.067 |
ACC (24) | Left | −0.5, 3.0, 8.4 | ACC (24) | 3.57 | 0.342* | −0.202 |
ACC (24)/M2 | Right | 0.9, 3.0, 8.4 | ACC (24)/M2 | 3.19 | 0.408** | 0.162 |
Insula | Left | −5.5, −1.0, 3.1 | DI/GI | 2.84 | 0.375** | −0.057 |
ACC (32) | Midline | −0.2, 4.0, 6.0 | ACC (32) | 3.19 | 0.365* | 0.172 |
according to Paxinos and Watson, 2005, given in mm x (0 = centre, left is negative), y (relative to Bregma), and z (ventral to dorsal); two peaks shown for bilateral regions.
Correlation coefficients between log-(50% VF thresholds) and the mean log-Jacobian determinant values for the cluster at post-surgery time points.
p < 0.05,
p < 0.01, two-tailed.
S1HL/M1, S1 hindlimb area/primary motor cortex, ACC (24), anterior cingulate cortex area 24, M2, secondary motor area, ACC (32), anterior cingulate cortex area 32. Insula includes granular (GI) and dysgranular (DI) insula cortex.