Table 1.

Base-case model assumptions for US incidence rates and costs by vaccine-preventable disease and age group

Disease and age groups	Number of persons (in millions)	Incidence rate (per 100,000)	Est. medical costs (per case)	Est. indirect costs (per case)a
Influenzab,c
50–64	61.8	6600	$1280	$604
65 and older	44.7	9000	$1867	$201
Pneumococcald
Bacteremiad
50–64	61.8	20	$32,204	$2707
65–74	25.2	37	$27,883	$1086
75–84	13.5	50	$24,433	$722
85 and older	6.0	64	$19,911	$652
Meningitisd
50–64	61.8	1	$35,188	$2707
65–74	25.2	2	$37,199	$1086
75–84	13.5	3	$32,957	$722
85 and older	6.0	4	$21,698	$652
Inpatient NPP d
50–64	61.8	57	$15,943	$2187
65–74	25.2	193	$15,887	$877
75–84	13.5	566	$15,419	$583
85 and older	6.0	1056	$14,470	$528
Outpatient NPP d
50–64	61.8	186	$585	$1041
65–74	25.2	370	$667	$418
75–84	13.5	620	$729	$278
85 and older	6.0	907	$801	$251
Herpes zostere,f,g
50–59	43.6	470	$1079	$3106
60–69	32.8	970	$1817	$4236
70–79	18.3	1300	$2537	$2997
80 and older	11.7	1500	$2537	$2819
Pertussish,i
50–64	61.8	292	$432	$593
65 and older	44.7	464	$432	$593

All costs were adjusted to 2013 U.S. dollars. NPP is non-bacteremic pneumococcal pneumonia caused by S. pneumoniae. ‘NPP inpatient’ refers to cases of NPP that require hospitalization where as ‘NPP outpatient’ refers to cases of NPP that do not require hospitalization

^a(Grosse et al., 2009)

^b(Molinari et al., 2007)

^c(Turner et al., 2006)

^d(Weycker et al., 2012)

^e(Tseng et al., 2011)

^f(Yawn et al., 2007)

^g(Singhal et al., 2011)

^h(Masseria & Krishnarajah, 2013)

ⁱ(Lee et al., 2004)