Table 2.

Receiver operating characteristics for individual steroid metabolites with sensitivity for detecting ACC >90 %

Metabolite	AUC	Cut-off value (μmol/24 h)	Sensitivity (%)	Specificity (%)
THS	1.000	2.35	100	99
P2	0.975	0.66	100	60
P3	0.960	1.45	100	61
E	0.960	2.47	100	53
A	0.839	0.35	100	14
THF	0.806	2.10	100	5
THE	0.700	3.20	100	4
PDL	0.884	0.15	96	26
11-KE	0.733	0.49	96	18
β-cortolone	0.793	0.45	96	7
α-cortolone	0.760	0.75	96	5
α-cortol	0.789	0.15	96	4
11-HA	0.699	0.15	96	2
11-HE	0.761	0.49	93	25
Polone	0.922	0.15	91	83

AUC area under curve, THS tetrahydro-11-deoxycortisol, P2 pregnanediol, P3 pregnanetriol, E etiocholanolone, A androsterone, THF tetrahydrocortisol, THE tetrahydrocortisone, PDL pregnanediolon, 11-KE 11-keto-etiocholanolone, 11-HA 11-hydroxy-androsterone, 11-HE 11-hydroxy-eticholanolone, Polone epi-pregnanolone