Table 5.
Patients’ characteristics according to outcome
| Parameter | Patients’ death | P value | |
|---|---|---|---|
| No | Yes | ||
| Patients number | 51 | 24 | |
| General | |||
| Gender (% Male) | 53 | 38 | 0.21 |
| Age (years) | 60 [50; 68] | 63 [60; 68] | 0.14 |
| Vasculitis | |||
| MPO-ANCA (%) | 65 | 35 | 0.31 |
| PR3-ANCA (%) | 78 | 22 | |
| Severe lung hemorrhage (%) | 29 | 39 | 0.39 |
| BVAS | 15 [14; 21] | 20 [17; 21] | 0.01 |
| Response to induction therapy | 76 % | 25 % | <0.0001 |
| Inflammation | |||
| Hemoglobin (g/dL) | 8.6 [7.7; 9.9] | 8.5 [7.4; 9.8] | 0.79 |
| WBC | 9400 [7600; 13900] | 10600 [7800; 18400] | 0.21 |
| ESR | 100 [78; 120] | 80 [61; 120] | 0.20 |
| Fibrinogen | 720 [578; 820] | 645 [525; 750] | 0.15 |
| Serum albumin | 3.7 [3.2; 4.0] | 3.2 [2.8; 3.6] | 0.008 |
| Kidney | |||
| Histopathologic class | |||
| Crescentic (%) | 49 | 58 | 0.5 |
| Focal (%) | 4 | 8 | |
| Mixed (%) | 33 | 29 | |
| Sclerotic (%) | 14 | 4 | |
| Serum creatinine (mg/dL) | 4.7 [3.0; 7.4] | 6.9 [4.1; 8.0] | 0.06 |
| Proteinuria | 0.9 [0.5; 2.2] | 0.8 [0.6; 2.2] | 1.00 |
| Hematuria | 230 [180; 670] | 365 [240; 1600] | 0.008 |
| Dialysis at presentation (%) | 22 | 38 | 0.15 |
Values are median [quartile 1; quartile 3] if not otherwise specified
PR3-ANCA patients positive for anti-proteinase 3 antibodies, MPO-ANCA patients positive for anti-myeloperoxidase antibodies, BVAS Birmingham Vasculitis Activity Score, WBC white blood cells, ESR erythrocite sedimentation rate