FIG. 3.

MCMV/CY pneumonitis is characterized by a massive expansion of MCMV-specific CD8+ T lymphocytes in the lung. (A) and (B) Representative flow cytometry for CD8, and pp89 tetramer surface expression on days 7, 14, and 21 MCMV- and MCMV/CY-treated mice. Quadrant values represent detected frequencies of each population, gating on lung mononuclear cells, and splenocytes, respectively. (C) and (D) Data points represent mean cell counts per lung±SEM, with p-values determined by t-test from individual mice with six to eight mice per group. *p<0.05.