Table 1.
Measure | Mean ± SD |
---|---|
SOAPP-R Total | 13.7±11.49 |
DELTA Drug Effect | 2.9±1.00 |
DELTA Drug Liking | 57.7±21.82 |
DELTA Take Again | 63.1±25.02 |
VAS Feeling High | 41.2±29.16 |
VAS Feeling Sedated | 48.3±31.20 |
VAS Feeling Elated | 37.1±29.09 |
VAS Feeling Down | 9.5±20.96 |
VAS Feeling Anxious | 10.7±18.54 |
VAS Feeling Good | 53.7±30.43 |
VAS Feeling Bad | 15.0±27.63 |
Placebo Acute Ischemic Pain – | |
MPQ-Sensory | 10.9±7.81 |
MPQ-Affective | 1.8±2.63 |
Tolerance (sec) | 294.6±172.15 |
Placebo Acute Thermal Pain – | |
MPQ-Sensory | 8.1±6.45 |
MPQ-Affective | 1.1±2.15 |
Tolerance (deg C) | 47.5±1.69 |
Morphine Effect on Acute Ischemic Pain – | |
MPQ-Sensory | −1.7±5.99 |
MPQ-Affective | −0.7±1.99 |
Tolerance (sec) | 38.84±126.56 |
Morphine Effect on Acute Thermal Pain – | |
MPQ-Sensory | −1.1±5.06 |
MPQ-Affective | −0.2±1.83 |
Tolerance (deg C) | 0.2±0.95 |
Baseline Chronic Pain Intensity – | |
MPQ-Sensory | 6.3±6.06 |
MPQ-Affective | 1.0±1.85 |
Morphine Effect on Chronic Pain – | |
MPQ-Sensory | −1.7±5.05 |
MPQ-Affective | −0.1±1.70 |
Note: DELTA and VAS values are presented for the morphine condition. For DELTA Drug Liking and Take Again, a value of 50 indicates a neutral response, with values greater than 50 indicating a positive response and values under 50 indicating a negative response. Negative values for morphine effects on acute and chronic pain ratings indicate reductions in pain with morphine relative to comparable placebo condition values. Positive values for morphine effects on acute pain tolerance indicate increased pain tolerance with morphine relative to placebo. Baseline chronic pain intensity values reflect the mean of the pre-drug values across the placebo and morphine laboratory sessions.