Table 3.
General linear models examining the relationship of OPRM1 allele A118G on overall pain severity six weeks after motor vehicle collision (MVC) among all men and women and among men and women with substantial peritraumatic distress after MVC
| Independent variablea | Beta | SE | P |
|---|---|---|---|
| In all women (n = 575) | |||
| A118G allele | −0.264 | 0.268 | 0.324 |
| Age | 0.013 | 0.009 | 0.146 |
| Education | −0.291 | 0.091 | 0.001 |
| Income | −0.185 | 0.068 | 0.007 |
| Pain at the time of initial evaluation | 0.044 | 0.006 | 0.000 |
| Pain prior to MVC | 0.014 | 0.051 | 0.780 |
| In women with peritraumatic distress (n = 256) | |||
| A118G allele | −0.925 | 0.375 | 0.014 |
| Age | 0.022 | 0.013 | 0.100 |
| Education | −0.170 | 0.135 | 0.205 |
| Income | −0.230 | 0.102 | 0.024 |
| Pain at the time of initial evaluation | 0.041 | 0.008 | <0.001 |
| Pain prior to MVC | 0.035 | 0.070 | 0.621 |
|
| |||
| In men (n = 373) | |||
| A118G allele | 0.827 | 0.352 | 0.019 |
| Age | 0.041 | 0.011 | 0.000 |
| Education | −0.197 | 0.115 | 0.086 |
| Income | −0.121 | 0.090 | 0.179 |
| Pain at the time of initial evaluation | 0.049 | 0.007 | <0.001 |
| Pain prior to MVC | 0.066 | 0.070 | 0.347 |
| In men with peritraumatic distress (n = 99) | |||
| A118G allele | 0.340 | 0.802 | 0.672 |
| Age | 0.070 | 0.025 | 0.006 |
| Education | 0.115 | 0.242 | 0.636 |
| Income | −0.255 | 0.169 | 0.132 |
| Pain at the time of initial evaluation | 0.039 | 0.010 | <0.001 |
| Pain prior to MVC | 0.041 | 0.117 | 0.728 |
Study site was also included in model as a categorical variable