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. 2015 Jun 29;10(6):e0131661. doi: 10.1371/journal.pone.0131661

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© 2015 Leonard et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — Knee joint tissues of MRL control, B6 control and B6 chimeric mice are immunopositive for Class 1 MHC H2Kk (arrows indicate typical immunopositive cells). Location of the cartilage injury in the femoral groove is indicated by the red asterisk. Scale bars all = 100μm. A. Bone marrow: engraftment of MRL/MpJ bone marrow into B6 chimeric mice shown by the presence of MHC H2Kk-immunopositive cells (arrows). B: MRL-derived H2Kk-positive cells are seen in the synovium of B6 chimeric mice (arrows); C: MRL-derived cells are present in bone marrow of B6 chimeras but not in cartilage or other intra-articular tissues (bottom right panel).