Figure 4. Reduced Ab production in Egr1-/- mice. WT and Egr1-/- mice were immunized with NP-KLH/alum, and serum was collected at 14 and 21 days after immunization. Titers of NP-specific IgG were detetmined by ELISA. Values represent the mean±SEM arbitrary unit (AU)/ml, pooled from three independent experiments (n=10~12 per group). p-values were determined using unpaired two-tailed Student's t-tests. ND, not detected.
