Table 1.
Longevity effects of temperature manipulation on various animal species
| Organism | Temperatures studied (in °C) | % increase in t 0.5 (from 5 °C drop unless otherwise specified) | Reference |
|---|---|---|---|
| Invertebrates (model organisms only) | |||
| D. melanogaster | 18–27 | 86 | (Miquel et al. 1976) |
| C. elegans | 15–25 | 75 | (Van Voorhies and Ward 1999) |
| Poikilothermic vertebrates | |||
| Cynolebias adloffi | 16 and 22 | 75 (t 0.45; for 6 °C drop) | (Liu and Walford 1966) |
| Cynolebias bellottii | 15 and 20 | 43 | (Liu and Walford 1975) |
| Nothobranchius furzeri | 22 and 25 | 14 (for 3 °C drop) | (Valenzano et al. 2006) |
| Nothobranchius rachovii | 20–30 | 57 | (Hsu and Chiu 2009) |
| Strain | Temperature decrease (in °C) | % increase in t 0.5 | Reference |
|---|---|---|---|
| Mammals (mice) | |||
| Hcrt-UCP2 (females) | 0.34 | 20 | (Conti et al. 2006) |
| Hcrt-UCP2 (males) | 0.3 | 12 | |
Only laboratory studies specifically manipulating temperature are included. When more than two temperatures were studied, values were averaged. Extreme temperatures in which pathological effects may play a role (McDougall and Mills 1997; Miquel et al. 1976; Van Voorhies and Ward 1999) were excluded from the results
t 0.5 is the median lifespan; t 0.45 is the age when 45 % of animals have died. See text for details