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. 2015 May 7;10(1):193–200. doi: 10.3892/etm.2015.2476

Figure 5.

Figure 5.

Effect of exogenous gene transfection with PUMA on Tau-induced apoptosis of HepG2 cells. Apoptotic cells of HepG2 were analyzed by flow cytometry. (A) control; (B) HA; (C) PUMA; (D) 160 mM Tau; (E) PUMA + Tau group; (F) 10µg/ml DDP and (G) the statistical analysis of the apoptosis rate of HepG2 cells. Data from triplicate experiments were collected on a histogram (n=4). *P<0.05 and **P<0.01, vs. control or HA groups; #P<0.05, vs. DDP group. Tau, taurine; DDP, cisplatin; PI, propidium iodide; FITC, fluorescein isothiocyanate; PUMA, p53 upregulated modulator of apoptosis; HA, pCEP4-(HA)2-C1.