Table 2.
One-component TFs with metal ion effectors.
| Effector | Regulator | Regulated system | PDB | Reference |
|---|---|---|---|---|
| MerRF | ||||
| Hg (II) | MerR | Mercury detoxification | ||
| Cu (I), Ag (I), Au (I) | CueR | Copper-exporting ATPase, CopA | 1Q05 (Cu), 1Q06 (Ag), 1Q07 (Au) | Changela et al. (2003) |
| Zn (II) | ZntR | ZntA Zn(II)/Cd(II) export gene | 1Q08 | Changela et al. (2003) |
| ArsRF | ||||
| As (III) | ArsR | Arsenic resistance | Busenlehner et al. (2003) | |
| Zn (II) | SmtB | Cellular resistance to excess zinc | 1R23 | Eicken et al. (2003) |
| Zn (II) | CzrA | Zinc resistance | 1R1V | Eicken et al. (2003) |
| Ni(II), Co(II) | NmtR | ATPase metal efflux pump | 2LKP | Lee et al. (2012) |
| Cd (II), Pb(II), Zn(II) | CadC | Heavy-metal efflux pump CadA | 1U2W | Ye et al. (2005) |
| DtxRF | ||||
| Fe (II), Ni(II) | DtxR | Diphteria toxin regulation | 1DDN | White et al. (1998) |
| Fe (II), Co(II), Ni(II) | IdeR | Iron uptake | 2ISY | Wisedchaisri et al. (2007) |
| Mn(II), Cd(II), Zn(II) | ScaR | Manganese uptake | 3HRT (Cd) 3HRU (Zn) | Stoll et al. (2009) |
| FurF | ||||
| Fe (II) | Fur | Iron uptake | 2W57 | Sheikh and Taylor (2009) |
| Zn (II) | Zur | Zinc-uptake | 4MTE | Gilston et al. (2014) |
| Ni (II) | Nur | Nickel homeostasis and anti-oxidative response | 3EYY | An et al. (2009) |
| NikRF | ||||
| Ni (II) | NikR | Nickel ABC-type transporter | 2HZV | Schreiter et al. (2006) |