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Therapeutic effects of miR-346 on mouse diabetic nephropathy. (A) miR-346 treatment induced physiological changes in db/db mice. The treatment was initiated at week 8. Each data-point represents the mean value of 3 observations (n=3). *P<0.05 vs. control. (B) Protective effect of miR-346 on the glomerular histology in db/db mice. db/db mice were sacrificed at week 16, and renal tissue sections were stained with Periodic acid Schiff. miR-346, microRNA-346.
