Table 4.

Genotypic and allelic frequency distribution of −384A/C and 584C/T polymorphic of the LIPG gene in patients and controls with CAD

		CAD n=287	Control n=367	p Value*	OR (95% CI)
LIPG −384A/C (rs3813082)
Genotype frequency	AA	184 (64.1%)	267 (72.8%)		Reference
	AC	90 (31.4%)	90 (24.5%)
	CC	13 (4.5%)	10 (2.7%)	0.051
	AC+CC	103 (35.9%)	100 (27.2%)	0.018	1.495 (1.071 to 2.085)
				0.071†	1.524 (0.964 to 2.410)†
Allele frequency	A	458 (79.8%)	624 (85.0%)		Reference
	C	116 (20.2%)	110 (15.0%)	0.013	1.437 (1.078 to 1.915)
LIPG 584C/T (rs2000813)
Genotype frequency	CC	160 (55.7%)	216 (58.9%)		Reference
	CT	116 (40.4%)	139 (37.9%)
	TT	11 (3.8%)	12 (3.3%)	0.711
	CT+TT	127 (44.3%)	151 (41.1%)	0.427	1.135 (0.831 to 1.552)
Allele frequency	C	436 (76.0%)	571 (77.8%)		Reference
	T	138 (24.0%)	163 (22.2%)	0.467	1.109 (0.856 to 1.436)

*Compared with controls.

†Adjusted by age, gender, TC, TG, HDL-C and LDL-C.

HDL-C, high-density lipoprotein cholesterol; LDC-C; low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride.