Table I.
Clinical backgrounds of the subjects by age group.
Characteristics | All patients (n=148) | Elderly (>75) (n=48) | Non-elderly (<75) (n=100) | P-value |
---|---|---|---|---|
Age, years (mean ± SD) | 68.0±10.0 | 78.6±3.1 | 62.9±7.8 | – |
Gender, male/female | 74/74 | 29/19 | 45/55 | 0.0791 |
BMI, kg/m2 (mean ± SD) | 22.8±3.5 | 22.4±3.0 | 23.1±3.7 | 0.2824 |
ASA score, no. | 0.0163a | |||
1/2/3 | 64/45/39 | 13/17/18 | 51/28/21 | |
Comorbidities, no. (%) | ||||
Overall | 73 (49.3) | 22 (45.8) | 51 (51.0) | 0.5562 |
Diabetes mellitus | 22 (14.9) | 5 (10.4) | 17 (17.0) | 0.2919 |
Cardiovascular disease | 34 (23.0) | 17 (35.4) | 17 (17.0) | 0.0127a |
Pulmonary disease | 17 (11.5) | 9 (18.8) | 8 (8.0) | 0.0628 |
Charlson index, no. | 0.2618 | |||
0/1/2/3/4 | 82/43/17/5/1 | 26/18/4/0/0 | 56/25/13/5/1 | |
Prior abdominal surgery, no. (%) | 19 (12.8) | 9 (18.8) | 10 (10.0) | 0.1363 |
Tumor location | 0.2331 | |||
Right colon | 44 | 19 | 25 | |
Transverse colon | 61 | 17 | 44 | |
Left colon | 16 | 3 | 13 | |
Rectum | 27 | 9 | 18 | |
Tumor size, mm (mean ± SD) | 31.2±16.4 | 34.8±19.1 | 29.5±14.7 | 0.0707 |
Pathological UICC stage | 0.6518 | |||
I/II/III/IV | 14/47/47/40/0 | 6/14/13/15/0 | 8/33/34/25/0 | |
pN positive, no. (%) | 40 (27.0) | 15 (31.2) | 25 (25.0) | 0.4229 |
Pretreatment CEA, ng/µl | 8.1±17.1 | 9.6±21.5 | 7.4±14.7 | 0.4840 |
Pretreatment CRP, mg/dl | 0.27±0.47 | 0.11±0.21 | 0.24±0.55 | 0.1512 |
Surgical procedure, no. | 0.2567 | |||
Ileocecal resection | 12 | 6 | 6 | |
Right colectomy | 40 | 15 | 25 | |
Transverse colectomy | 7 | 0 | 7 | |
Left colectomy | 11 | 2 | 9 | |
Sigmoidectomy | 34 | 11 | 23 | |
Anterior resection | 44 | 14 | 30 |
Statistically significant differences. SD, standard deviation; BMI, body mass index; UICC, Union for International Cancer Control; ASA, American Society of Anesthesiology; pN, pathological node; CEA, carcinoembryonic antigen; CRP, C-reactive protein.