Figure 1.

Combined treatment with cisplatin and bortezomib inhibits cell proliferation of T24 cells. Graphical representation of water soluble tetrazolium salt assay, indicating percentage change in cell viability in T24 cells treated with (A) cisplatin (0, 0.5, 1, 2.5, 5, 10 and 20 mM), (B) bortezomib (0, 1, 5, 7.5, 10, 25, 50, 100, 200 and 300 nM) and (C) cisplatin plus bortezomib for 24 h. Data points represent the mean ± standard deviation of triplicate experiments. *IC₅₀ value. C, cisplatin; B, bortezomib.