Kaplan-Meier survival curves for CD147 and MMP-2 (Panel 1), ER (Panel 2) and PR (Panel 3) expression in patients with EEC. (A) CD147 and MMP-2 double negative expression; (B) CD147 negative, MMP-2 positive expression; (C) CD147 positive, MMP-2 negative expression; and (D) CD147 and MMP-2 double positive expression. Survival for patients with B subtypes was significantly increased compared with all other subtypes (P<0.01). EEC, endometrioid endometrial carcinoma; CD147, extracellular matrix metalloproteinase inducer; MMP-2, matrix metalloproteinase-2; ER, estrogen receptor; PR, progesterone receptor.