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. 2015 May 6;10(1):342–348. doi: 10.3892/ol.2015.3177

Table I.

Association analyses between the expression levels of CD147 and MMP-2 and the clinicopathological characteristics of endometrioid endometrial cancer.

CD147 expression MMP-2 expression


Clinicopathological variable Patients, n Low, n High, n χ2 P-value Low, n High, n χ2 P-value
All cases 107 59 48 58 49
Age, years 6.24 0.009 9.67 0.002
  >60 46 19 27 17 29
  ≤60 61 40 21 41 20
FIGO stage 0.445 0.505 7.316 0.007
  Low (I/II) 77 44 33 48 29
  High (III/IV) 30 15 15 10 20
Histological grade 1.611 0.204 6.669 0.010
  Low (G1 or 2) 84 49 35 51 33
  High (G3) 23 10 13 7 16
Lymph node metastasis 6.801 0.009 2.668 0.102
  Negative 74 47 27 44 30
  Positive 33 12 21 14 19
Depth of myometrial invasion 3.394 0.065 4.348 0.037
  <50% 66 41 25 41 25
  ≥50% 41 18 23 17 24
ER expression 10.025 0.002 3.128 0.077
  Low 60 25 35 28 32
  High 47 34 13 30 17
PR expression 2.155 0.142 7.962 0.005
  Low 54 26 28 22 32
  High 53 33 20 36 17

FIGO, International Federation of Gynecology and Obstetrics; ER, estrogen receptor; PR, progesterone receptor; CD147, extracellular matrix metalloproteinase inducer; MMP-2, matrix metalloproteinase-2.