Table 2.
Serum levels of alpha-fetoprotein (AFP) in cirrhotic patients with and without HCC, and the relation to clinical features (Child-Pugh class and BCLC stage)
| AFP (ng/mL) | Group I | Group II | p-value |
|---|---|---|---|
| (Cirrhosis) | (Cirrhosis and HCC) | ||
| 3.00 (0.90-17.00) | 11.00 (1.30-431272.00) | <0.001* | |
| Child-Pugh class | 0.627 ** | ||
| A | 2.50 (1.10-13.00) | 10.00 (1.30-2159.00) | |
| B | 3.40 (1.10-5.60) | 14.00 (1.60-431272.00) | |
| C | 3.10 (0.90-17.00) | 12.45 (1.40-8251.00) | |
| BCLC Stage a | 0.007 ** | ||
| 0 | 6.15 (5.90-6.40) | ||
| A | 3.20 (1.30-242.00) | ||
| B | 31.00 (2.80-431272.00) | ||
| C | 225.00 (8.70-7392.00) | ||
| D | 255.00 (3.30-8251.00) |
*p - Value by Mann–Whitney U test for comparison of serum AFP between two groups
**p - Value by Kruskal-Wallis test for comparison of serum AFP across Child-Pugh classes and BCLC stages
aBarcelona Clinic Liver Cancer