Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 30;12:55. doi: 10.1186/s12977-015-0179-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Brener et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Sequence changes within Gag epitopes restricted by HLA-B*14, B*27 and B*57 identified by ultra-deep sequencing of an HIV transmission pair aligned to CRF01_AE clade consensus (bold) and B clade consensus sequence (grey). The frequency of minor variant haplotypes at the HLA-B*57 Gag-ISW9, HLA-B*57 Gag-KF11, HLA-B*57 Gag-TW10, HLA-B*27 Gag-KK10, and HLA-B*14 Gag-DA9 epitopes above a cut-off of 1% are shown. Depth of coverage ranges from 560 to 240,000 reads. Position 146 (flanking HLA-B*57 Gag-ISW9), associated with selection of an HLA-B*57/58:01-selected A146P processing mutation in B clade infection, is also shown. Minor variant frequencies are rounded off to the nearest 1%.