Table 1.
Putative biosynthetic gene clusters for specialised metabolites
antiSMASH Cluster No. | antiSMASH type descriptor | Position (manually annotated clusters in italics) | Our annotation (based on Ref.) | |
---|---|---|---|---|
From | To | |||
1 | T1pks | 99264 | 143430 | |
Not identified | 160425 | 189028 | Hygromycin A [11, 44] | |
2 | T1pks | 191701 | 240196 | |
3 | T1pks-nrps | 324784 | 392261 | |
4 | Nrps | 379508 | 426758 | |
5 | T3pks | 416888 | 458084 | |
6 | Bacteriocin | 572464 | 582679 | |
7 | Terpene | 598795 | 619823 | |
Not identified | 684373 | 654830 | Lasso-peptide 2 | |
8 | Nrps | 714060 | 794426 | |
9 | Terpene | 1056004 | 1076960 | |
10 | T2pks-transatpks-nrps | 1075399 | 1155931 | Halogenated polyketide [Razmilic et al.] |
11 | T1pks-terpene | 1211049 | 1289829 | Chaxamycin [Castro et al.] |
12 | T1pks | 1497127 | 1544539 | |
13 | Terpene | 1624097 | 1645110 | |
14 | T1pks-siderophore | 1776281 | 1833813 | |
15 | Terpene | 1972277 | 1994487 | |
16 | Bacteriocin | 2013690 | 2025087 | |
17 | Siderophore | 2293580 | 2305424 | Highly conserved |
18 | Nrps-t1pks | 2668194 | 2719415 | |
19 | T3pks | 2937137 | 2978264 | |
20 | Terpene | 3056325 | 3058819 | Albaflavenone [45, 46] |
Not identified | 3560196 | 3564842 | Lasso-peptide 1 | |
21 | Siderophore | 5237176 | 5244356 | Desferrioxamine E [11, 47, 48] |
22 | Melanin | 5330379 | 5340933 | |
23 | Amglyccycl-butyrolactone | 5385171 | 5417416 | |
24 | Ectoine | 6176293 | 6186691 | |
25 | Other | 6710095 | 6751819 | |
26 | T3pks | 6822979 | 6864043 | |
27 | T1pks | 7141058 | 7240871 | Chaxalactin [11, Castro et al.] |
28 | T1pks | 7355977 | 7439461 | |
29 | Other | 7486047 | 7529121 | |
30 | Terpene-t2pks | 7530162 | 7588405 | |
31 | Terpene | 7744176 | 7768730 | |
Not identified | pSLE2 103389 | pSLE2 105999 | Lasso-peptide 3 |