Table 2.
COG functional categories. COG (Clusters of Orthologous Genes) functional categories of chromosomal protein codding sequences identified in S. leeuwenhoekii chromosome, and from S. coelicolor for comparison (as calculated by BASys [25] for both genomes)
| Streptomyces leeuwenhoekii | Streptomyces coelicolor | |||
|---|---|---|---|---|
| COG functional categories | Percentage | Number | Percentage | Number |
| Energy production and conversion | 4 | 270 | 4.1 | 317 |
| Cell division and chromosome partitioning | 0.5 | 30 | 0.4 | 31 |
| Amino acid transport and metabolism | 6 | 400 | 5.1 | 395 |
| Nucleotide transport and metabolism | 1.3 | 89 | 1.2 | 93 |
| Carbohydrate transport and metabolism | 6.5 | 433 | 6.5 | 503 |
| Coenzyme metabolism | 2.3 | 154 | 2.2 | 170 |
| Lipid metabolism | 3.7 | 250 | 3.3 | 255 |
| Translation, ribosomal structure and biogenesis | 2.7 | 182 | 2.5 | 193 |
| Transcription | 7.3 | 493 | 8.5 | 658 |
| DNA replication, recombination and repair | 2.9 | 193 | 2.9 | 224 |
| Cell envelope biogenesis, outer membrane | 3 | 204 | 2.9 | 224 |
| Cell motility | 0.1 | 5 | 0.1 | 8 |
| Posttranslational modification, protein turnover, chaperones | 1.9 | 127 | 1.8 | 139 |
| Inorganic ion transport and metabolism | 2.3 | 154 | 2.7 | 209 |
| Secondary Structure | 2.8 | 186 | 1.9 | 147 |
| General function prediction only | 6.9 | 460 | 7.4 | 572 |
| COG of unknown function | 3.6 | 243 | 3.6 | 278 |
| Signal Transduction | 3.8 | 256 | 4.2 | 325 |
| Unknown | 36.6 | 2458 | 36.7 | 2839 |