Table 2.
Characteristics of 47 hepatocellular carcinoma patients with initial extrahepatic metastases
| Number | Percent | |
|---|---|---|
| Male/Female | 38/9 | |
| Age range | 40–80 years | |
| Median age | 60 years | |
| HCV | 47 | 100 |
| HBV | 1 | 2.1 |
| Elevated AFP | 22 | 46.8 |
| Cirrhosis | 36 | 76.6 |
| Hepatic focal lesion: | ||
| -Solitary | 38 | 80.9 |
| -Multiple | 9 | 19.1 |
| Site of metastases: | ||
| - Bones | 17 | 36.2 |
| -Lymph nodes | 9 | 19.1 |
| - Soft tissue | 7 | 15 |
| - Omentum | 7 | 15 |
| -Maxillary sinus | 2 | 4.2 |
| -Adrenal gland | 2 | 4.2 |
| -Brain | 2 | 4.2 |
| -Skin | 1 | 2.1 |
| Pattern of HCC growth : | ||
| -Trabecular (plate like) | 8 | 17 % |
| - Pseudoglandular (acinar) | 2 | 4.3 % |
| -Solid | 10 | 21.3 % |
| -Mixed patterns | 27 | 57.4 % |
| Grade: | ||
| - Well differentiated | 0 | 0 % |
| - Moderately differentiated | 17 | 36.2 % |
| - Poorly differentiated | 30 | 63.8 % |
HCV hepatitis C virus, HBV hepatitis B virus, AFP α fetoprotein