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. 2015 Jun 30;15:205. doi: 10.1186/s12906-015-0730-4

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© Tan et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — mRNA levels of HT-29 cells treated with WBR. Expression of a AXIN1, b casein kinase 1 (CK1), c glycogen synthase kinase 3β (GSK3β), and d adenomatous polyposis coli (APC) in Wnt signaling at mRNA levels in HT-29 cells incubated with WBR (n = 3). Value with different superscript letter indicates significant difference between groups by Tukey’s test (P < 0.05). AXIN1 gene did not significantly differ between the control cells and those from the groups treated with 32 or 64 μg/mL WBR (P > 0.05). CK1 mRNA level in the groups treated with 32 and 64 μg/mL WBR was significantly increased compared with the control (P < 0.05). GSK3β mRNA level in the group treated with 64 μg/mL WBR was significant decreased compared with the control (P < 0.05). APC gene in the groups treated with WBR was significantly elevated compared with the control (P < 0.05)